Peptide Therapy

Peptides are one of the most exciting tools in modern integrative medicine—not because they’re magic, but because they speak the same “language” your body already uses to heal. At Creekside, we use peptide therapy to help nudge biology back toward balance: calmer inflammation, sturdier gut lining, better recovery, and steadier metabolism. When paired with sleep, nutrition, movement, and stress care, peptides can act like circuit-breakers that help your system reset.

What are peptides?
Peptides are short chains of amino acids—tiny messengers your cells naturally recognize. Instead of overpowering your body, they signal specific pathways: tissue repair, mitochondrial energy, growth-hormone pulses during sleep, or tighter gut junctions. Because they’re targeted, many patients experience benefits without feeling “wired,” sedated, or dependent on a daily stimulant.

Why peptide therapy now?
Chronic stress, poor sleep, processed food, and over/under-training create a background of metaflammation—a constant “danger signal” that can show up as joint aches, brain fog, stubborn belly weight, or a sensitive gut. Peptides help us address upstream physiology (barrier integrity, mitochondrial efficiency, circadian signaling) rather than chasing symptoms alone. Our goal isn’t to stack more pills; it’s to restore homeostasis.

When we consider peptides
Peptides aren’t for everyone, and they’re never a stand-alone fix. We consider them when a personalized plan would benefit from targeted signaling, such as:

Tissue recovery: nagging tendon/ligament pain, slow-to-heal soft tissue, or high training loads
Gut support: bloating, sensitivity, or “leaky gut” patterns while you complete an elimination or anti-inflammatory plan
Mitochondrial energy: low stamina, age-related fatigue, or difficulty tolerating exercise progression
Metabolic reset: insulin resistance, weight loss plateaus, or “skinny-fat” body composition
Healthy aging: skin integrity, connective tissue quality, sleep recovery, and resilience

Examples you’ll hear us discuss

BPC-157: supports mucosal and microvascular repair; often paired with physical therapy for overuse injuries or with an elimination diet for gut comfort.
KPV: a gut-calming tripeptide that helps down-shift inflammatory signaling; we use it during barrier-repair phases.
GHK-Cu: widely studied for skin/ECM remodeling and “pro-repair” gene signaling; available in topical and oral forms.
MOTS-c: a mitochondrial peptide that can improve activity tolerance and metabolic flexibility in older adults.
CJC-1295/Ipamorelin: bedtime micro-pulses that support growth-hormone rhythms, aiding recovery and sleep quality.
GLP-1/GIP class: for insulin resistance and weight—always paired with nutrition, protein goals, and strength training.

We’ll never push every peptide on every patient. The art is choosing the one or two that best match your goals and biology, then giving them the right environment to work.
How we use peptides at Creekside

Assess & anchor the basics. We screen sleep, stress, diet quality, protein intake, and movement. If your “foundation” is shaky, peptides won’t stick.
Barrier-first when needed. Many chronic issues begin with gut permeability. We often start with a short, gluten-free or anti-inflammatory phase plus zinc-carnosine, magnesium, omega-3s, and a gut-support peptide (e.g., KPV or BPC-157).
Layer precisely. For persistent fatigue, we may add MOTS-c pulses. For recovery, a CJC/Ipam bedtime plan. For skin/soft-tissue support, GHK-Cu. For metabolic goals, we decide together if a GLP-1/GIP agent belongs—never as a substitute for habits.
Monitor and iterate. We track simple metrics you can feel and measure: morning stiffness, stool form, step count, resistance volume, sleep quality, and select labs (e.g., hs-CRP, ApoB, ferritin, thyroid).

What results should you expect?
Most patients who benefit notice changes between weeks 2–6—calmer joints or gut, better day-after recovery, a bump in walking tolerance, or deeper sleep. Results vary; the biggest wins come when peptides are stacked with behavior (protein targets, gentle progressive strength, light exposure, and consistent bedtime).
Safety, sourcing, and suitability

Many peptides are not FDA-approved and are used off-label under physician supervision. We use vetted sources and discuss quality and cost transparently.
Not for pregnancy or breastfeeding. We use caution in anyone with a history of hormone-sensitive cancers or active malignancy.
Tell us about all medications (especially blood thinners, immunosuppressants) and supplements. We coordinate with your other clinicians when needed.
Peptides are tools—not replacements—for nutrition, sleep, movement, and stress work.

Is peptide therapy right for you?
If you’re curious, we’ll start with a quick discovery visit to map your goals and choose a simple, time-boxed plan—usually one peptide + one lifestyle lever for 8–12 weeks. From there, we adjust based on your progress, not hype.

Ready to explore peptide therapy the Creekside way?
Book a Peptide Consult or ask your clinician at your next visit. We’ll decide together if a precise signal—at the right time—can help your body do what it was designed to do: heal and adapt.